PROPOFOL
Si Disponible: Dispensado al Día Siguiente
Envío Gratis
Dentro de México
Requiere Receta Médica
Este Medicamento requiere prescripción médica de su médico, clínica, hospital o terapeuta.
Propofol
Clase: Anestésico, Agentes de EM.
Cómo Suministrado: -Emulsión intravenosa para inyección: 1 ml, 10 mg, 20 mg.
DESCRIPCIÓN:
Anestésico general y sedante intravenoso. Se utiliza para la inducción y el mantenimiento de la anestesia general, la sedación con atención anestésica monitorizada (MAC), la sedación combinada y la anestesia regional y la sedación en la unidad de cuidados intensivos (UCI) de pacientes con ventilación mecánica.
Description
Propofol
| Propofol Brands | ||||
| Brand Name | Manufacturer | Strength | Packaging | Certifications |
| Diprivan | AstraZeneca Pharma India | 10 mg/mL (1%) | 10 mL vials | WHO-GMP, EU-GMP |
| Diprivan | AstraZeneca Pharma India | 10 mg/mL (1%) | 20 mL vial | WHO-GMP, EU-GMP |
| Diprivan | AstraZeneca Pharma India | 10 mg/mL (1%) | 50 mL vial | WHO-GMP, EU-GMP |
| Critifol | Abbott Healthcare Pvt | 10 mg/mL (1%) | 20 mL vials | WHO-GMP |
| Critifol | Abbott Healthcare Pvt | 10 mg/mL (1%) | 50 mL vials | WHO-GMP |
| Fresofol | Fresenius Kabi India Pvt | 10 mg/mL (1%) | 50 mL vials | WHO-GMP, ISO |
| Neorof | Neon Laboratories Ltd. | 10 mg/mL (1%) | 20 mL, vials | WHO-GMP |
| Neorof | Neon Laboratories Ltd. | 10 mg/mL (1%) | 50 mL vials | WHO-GMP |
| Propofol Inj | Generico Various Mfg's | 10 mg/mL (1%) | 10 mL vials | WHO-GMP |
| Propofol Inj | Generico Various Mfg's | 10 mg/mL (1%) | 20 mL vials | WHO-GMP |
| Propofol Inj | Generico Various Mfg's | 10 mg/mL (1%) | 50 mL vials | WHO-GMP |
| Propovan | Samarth Life Sciences Pvt | 10 mg/mL (1%) | 10 mL, vials | WHO-GMP |
| Propovan | Samarth Life Sciences Pvt | 10 mg/mL (1%) | 20 mL vials | WHO-GMP |
| Rofol | Gland Pharma Ltd. | 10 mg/mL (1%) | 20 mL vials | WHO-GMP |
| Celofol | Celon Laboratories Ltd. | 10 mg/mL (1%) | 20 mL vials | WHO-GMP |
| Troypofol | Wellona Pharma | 10 mg/mL (1%) | 10 mL vials | WHO-GMP, ISO |
| Troypofol | Wellona Pharma | 10 mg/mL (1%) | 20 mL vials | WHO-GMP, ISO |
| Troypofol | Wellona Pharma | 10 mg/mL (1%) | 50 mL vials | WHO-GMP, ISO |
| USA | Fresenius, Kabi | 10 mg/mL | 100 mL vial | WHO-GMP-FDA |
| USA | Kabi, Sagent | 10-50 mL Vials | 200 mL vials | WHO-GMP-FDA |
| USA | Hikma | 10 - 20 mL | 20 mL vials | WHO-GMP-FDA |
Propofol
Phonetic Pronunciation: PROE-poe-folType / Category
Short-acting Intravenous General Anesthetic – Central Nervous System DepressantProduct Description
Propofol is a rapidly acting, lipophilic intravenous anesthetic agent used for the induction and maintenance of general anesthesia and sedation. Its primary mechanism involves potentiation of the GABA-A receptor, enhancing inhibitory neurotransmission and leading to dose-dependent sedation and hypnosis. Due to its rapid onset and short duration of action, Propofol is widely utilized in surgical anesthesia, intensive care sedation, and procedural sedation. It is supplied as an oil-in-water emulsion and must be administered intravenously under strict medical supervision.Available Presentations
- Strength: 10 mg/mL (1%), 20 mg/mL (2%) – in select formulations
- Formulation: Sterile emulsion for intravenous injection; lipid-based with soybean oil, glycerol, and egg lecithin
- Volume per Vial/Ampoule: 20 mL, 50 mL, 100 mL
- Packaging: Glass vials, ampoules, or infusion bottles (non-PVC); boxed in 10s or 25s
- Is Dilution Required?: Optional; may be diluted with 5% Dextrose or 0.9% NaCl if needed
- Storage Conditions: Store at 2°C to 25°C; do not freeze; use immediately after opening
Uses
- Primary Uses: Induction and maintenance of anesthesia; ICU and procedural sedation
- Off-Label / Investigational: Status epilepticus, severe agitation (palliative), migraine rescue
Indications
- General anesthesia for surgical procedures
- Monitored anesthesia care sedation
- ICU sedation for intubated adults
- Procedural sedation (e.g., endoscopy, colonoscopy)
Pediatric Use
Approved for induction/maintenance in children over 3 years. ICU sedation in pediatric patients is off-label due to risk of metabolic complications.Regulatory and Safety Profile
- ATC Code: N01AX10
- WHO Essential Medicines List: ✔️ Yes
- Pharmacologic Class: Intravenous Anesthetic / Hypnotic
- Black Box Warning (USA): Not approved for ICU sedation in pediatric patients
- Contraindications: Hypersensitivity to propofol or components (soy, egg), disorders of fat metabolism
- Common Side Effects: Hypotension, apnea, bradycardia, injection site pain, hypertriglyceridemia
- Monitoring Parameters: ECG, blood pressure, oxygen saturation, ABG, serum triglycerides (if prolonged use)
